Strumenti Web


BBMRI.it mette a disposizione delle biobanche e dei ricercatori un elenco ragionato di strumenti web utili per le attività di ricerca che prevedono l'uso di campioni biologici. Alcuni di questi sono stati prodotti durante la fase preparatoria di BBMRI o di altre infrastrutture europee. Le descrizioni sono in inglese perché tratte dai siti web. Segnalateci (italy@bbmri.it) altri strumenti utili e li aggiungeremo alla lista.

 

MIAPAR

 

MIAPAR is intended to be used as a guideline for experimentalists who wish to unambiguously describe protein affinity reagents and their protein targets (including but not limited to Ab/Ag interactions). It specifies the minimum amount of information which should be present, or directly traceable, in any publication, database entry or commercial catalogue describing either the production or use of affinity reagents such as antibodies, aptamers, protein scaffolds etc. The MIAPAR paper is out to consultation and unsolicited comments are welcome; please send any feedback to orchard[@]ebi.ac.uk. The Minimum Information about a Protein Affinity Reagent MIAPAR is available for public comment.

 

MOLMETH

 

Molmeth, the Molecular Methods Database, is a free and powerful tool. It has unique collaborative features for researchers to publish and improve methods or lab protocols online.

 

CLIMA

 

Cross-contamination of human cell lines is a frequent cause of scientific misrepresentation. A short tandem repeat profile reference standard was proposed in 2001 by the leading cell banks and five large research institutes, who tested 253 human cell lines. The editorial "Obligation for cell line authentication: Appeal for concerted action" published in 2010 in the Intl Journal of Cancer encouraged journals and funding agencies to require proper authentication of all cell lines. STR authentication is now required by many leading oncological journals.

The Cell Line Integrated Molecular Authentication database (CLIMA) links available authentication data to actual cell lines distributed by cell banks. It was designed in the frame of the Cell Line Data Base, a well-known reference information source on human and animal cell lines. CLIMA includes STR profiling obtained by using different platforms; the end users can retrieve data on cell line authentications performed by different cell banks.

 

BioSharing

 

BioSharing works to map the landscape of community developed standards in the life sciences, broadly covering biological, natural and biomedical sciences. BioSharing's goal is to ensure standards are informative and discoverable, monitoring their:

  • development, evolution and integration;
  • implementation and use in databases; and
  • adoption in data policies by funders and journals.

As part of the growing movement for reproducible research, a growing number of community-driven standardization efforts are working to make data along with the experimental details available in a standardized manner. BioSharing works to serve those seeking information on the existing standards, identify areas where duplications or gaps in coverage exist and promote harmonization to stop wasteful reinvention, and developing criteria to be used in evaluating standards for adoption (see straw man proposal). - See more

 

Legalpathways

 

The objective of this platform is to serve as a dynamic, online, grass roots platform for sharing, discussing, validating and issuing authoritative and reliable legal forms and standards to aid the BBMRI community in navigating the legal pathways that govern its pan European, cross border, multi-jurisdictional infrastructure and operations. The platform is to unearth any existing knowledge, expertise and templates currently in use by (prospective) BBMRI Members and Partners.

 

hSERN

 

Human sample exchange regulation navigator, a web based information tool on legal requirements for exchanging biological samples

 

MIABIS

MIABIS (Minimum Information About Biobank data Sharing) represents the minimum information required to initiate collaborations between biobanks and to enable the exchange of biological samples and data. The aim is to facilitate the reuse of bio-resources and associated data by harmonizing biobanking and biomedical research. The attributes are defined in accordance with epidemiological literature and terminology. MIABIS consists of three "core" components: Biobanks and Samples Collections and Study. Additional components currently under evaluation include, OMICS, Participant, Rare diseases, Samples and Sample Quality.